Department of Pharmacology
2007 publications
Abdel Galil AG, El-Sawy MM, Saad EI, Omar AG, El-Deeb NM and Helmy MM. α-Tocopherol Enhances Vascular Antioxidant Status and Preserves Vascular Integrity in Cyclosporin A-Treated Rats. Alex J Pharm Sci, 21, pp 145-152. Sept. (2007).
- Abdel-Galil AG., Saad EI, Raslan HS, El-Gowelli HM. Evaluation of Chamomile oil, Basil oil & Echinacea root extract in the acceleration of healing of experimentally induced wounds in rats. J. Egypt Pharmacol Exp Ther 28, pp19 – 51 (2007)El-Bassiouni EA, Helmy MH, Saad EI, Kamel MA , Abdel-Meguid E, Hussein HSE. Modulation of the antioxidant defence in different developmental stages of schistosoma mansoni by praziquantel and artemether. Brit J Biomed Sci 64, p 168, (2007)
El-Metwally MA, Sharabi FM, Daabees TT, Senbel AM and Mostafa T. Involvement of alpha-receptors and potassium channels in the mechanism of action of sildenafil citrate. International Journal of Impotence Research 19, pp 551 - 557 (2007)
2008 publications
El-Mas MM, El-gowilly SM, Goher EY, and Ghazal AM. Pharmacological characterization of cellular mechanisms of the renal vasodilatory effect of nicotine in rats. Eur J Pharmacol 588, pp 294–300 (2008).
El-Mas MM, Fan M and Abdel-Rahman AA. Endotoxemia-mediated facilitation of cardiac iNOS expression accounts for the hypotensive effect of ethanol in female rats. J Pharmacol Exp Ther 324, pp 368-375 (2008)
El-gowilly SM, Ghazal AM, Goher EY, and El-Mas MM. Exacerbation by nicotine of the cyclosporine-induced impairment of β-adrenoceptor-mediated renal vasodilation in rats. Clin Exp Pharmacol Physiol, (2008) In Press.
Tombary AA, Mohsen A, Omar ME, Eshba NH, Rostom SA, Ragab HM and Saad EI. Synthesis and acetylcholinesterase inhibitory activity of novel tetrahydroquinoline and pyrazol [3,4 β]-tetrahydroquinoline derivatives as potential agents for treatment of Alzheimer disease. Alex J Pharm Sci 22(1), (2 008).
Senbel AM and Mostafa T: Yohimbine enhances the effect of sildenafil on erectile process in rats. International Journal of Impotence Research 20, pp 409–417 (2008)
Nasr M, El-Gowilly S, El-Mas M. Equipotent effects of mosconidine and simvastatin in rats exposed to cigarette smoke. Egyp J Exper Pharmacol (2008) in press.
Department of Pharmaceutical Microbiology
2007 publications
Fawzi MA, Abou Shleib HM, Abolmagd E and Youssef AA. In vitro study on some factors influencing the antimicrobial activity of pemulen. Alex J Pharm Sci, 21(2), pp 117-23 (2007)
Abdel-Fattah YR, El-Enshasy H, Anwar M, Omar HM, Abolmagd E and Abou Zahra R. Application of factorial experimental designs for optimization of cyclosporine A production by Tolypocladium inflatum in submnerged culture. J Microbiol and Biotechnol 17(12), pp 1930-1936 (2007)
El-Enshasy H, Beshay UI, El-Diwany AI, Omar HM, El-Kholy AG and El-Najar R. Rifampicin production by Amycolatopsis mediterranei in batch and repeated cultures using immobilized cells in alginate-modified beads. Journal of Applied Sciences 7(10), pp 1381-1389 (2007)
Saleh SM and Kassem MA. Respiratory pathogens colonization on tongue surface of institutionalized elderly in Alexandria Egyptian Dental Journal (October 2007)
Kassem MA, Fanaki NH, Fawzi MA and Dabbous FSE. Influence of aqueous herbal extracts on the antimicrobial activity of some antibiotics against clinical microbial isolates. New Egyptian Journal of Microbilogy (September 2007)
2008 publications
El-Khouly AE, Abou Shleib HM, El guink NM, and El-Ammori MI. Design of triple antibiotic combination system effective against resistant clinical strains of pseudomonas aeruginosa. Egyptian Journal of microbiology, in press
Aggag ME, Fawzi MA, Saeed HM and Abdel Moneim NM. In vitro bacterial activity of cefepime, combined with ciprofloxacin, imipenem, tobramycin and amikacin against extended spectrum B-lactamases producing organisms. Egyptian Journal of microbiology, in press.
El-Enshasy H, Abdel Fattah Y, Atta A, Anwar M, Omar H, Abolmagd E and Abou Zahra R. Kinetics of cell growth and cyclosporine A product by Tolypocladium inflatum when scaling up from shake flask to bio reactor. Microbiol and Biotechnol. 18(1), pp 128- 134 (2008)
Omar H. Comparative bactericidal activity of five fluoroquinolones used in ophthalmology and their combinations with anti-inflammatory eye drops against ocular bacterial isolates. N. Egypt J Microbiol, 19, pp 93-121(2008)
Department of analytical chemistry
2007 publications
Mabrouk MM, Moneeb MS, Kamal AH and Wahbi AA. Simultaneous determination of paracetamol and ibuprofen in their tablets by chemometric spectropohotometry and HPLC. Bull. Fac.Pharm.CairoUniversity. vol 45 (2), pp 187 – 202 (2007).
Abdel-Hay MH, Galal SM and Ragab MA. Application of Derivative and Derivative-ratio Spectrophotometry in the Determination of a Binary Mixture of Naproxen and Diflunisal and a Ternary Mixture of Orphenadrine, Caffeine and Aspirin. Taiwan Pharmaceutical Journal, 59, pp 157-170 (2007).
Sabry SM. Polarographic and Voltammetric Assays of Sulfonamides as α-Oxo-γ-Butyrolactone Arylhydrazones. Anal. Lett., 40, pp 233-256 (2007).
2008 publications
Youssef RM.Validated Stability-indicating Methods for the Determination of Nizatidine in Presence of Its Sulphoxide Derivative. The Journal of AOAC International, 91(1) pp 73-82 (2008).
Youssef RM and Maher HM. A New Hybrid Double divisor Ratio Spectra Method for the Analysis of Ternary Mixtures. Spectrochimica Acta Part A, (2008) In press.
Maher HM and Youssef RM. Simultaneous Determination of Ternary Drug Mixtures Using Square Wave Polarography Subjected to Non-parametric and ChemometricPeak Convolution. Chemometrics and Intelligent Laboratory Systems, (2008) In press.
Hassan EM, Khamis EF, El-Kimary EI, Barary MA. Development of a differential pulse voltametric method for the determination of silymarin / vitamin E acetate mixture in pharmaceuticals. Talanta, 74 , pp 773-778 (2008).
Abdel-Hay MH, Hassan EM, Gazy AA and Belal TS. Kinetic spectrophotometric analysis and spectrofluorimetric analysis of ciprofloxacin hydrochloride and norfloxacin in pharmaceutical preparations using 4- chloro-7-nitrobenzo-2-oxa-1,3-diazole (NBD-Cl), Journal of Chinese Chemical Society, accepted (2008)
Hassan EM, Khamis EF, El-Kimary EI, Barary MA, Analysis of three hepatoprotectant binary mixtures containing silymarin in pharmaceutical preparations, Mansoura J.P.S.24,(1), 9-31 (2008)
Belal SF, Haggag RS and Shaalan RA. The use of an aromatic substitution reaction in the spectrophotometric determination of Selected Amino or Thiol Containing Drugs, Journal of Food and Drug Analysis, vol. 16, No. 1, (2008).
Belal SF, Haggag RS and Shaalan RA. Differential pulse polarographic Determination of clonidine hydrochloride and fosinopril sodium in pharmaceutical preparations through labelling using nitro derivatives. Bull Fac. Pharm. Cairo Univ., 46(1), pp 271-282, (2008).
Haggag R, Belal S and Shaalan R. Derivatization with 4-Chloro-7-nitro-2,1,3-benzoxadiazole for the spectrophotometric and differential pulse polarographic determination of acetylcysteine and captopril, Sci Pharm 76 : pp 33- 48, (2008).
Haggag R, Belal T and Shaalan R. Stability indicating methods for the determination of Mexiletine hydrochloride in presence of its related substance : 2,6- Dimethylphenol. Determination of 2,6- Dimethylphenol in presence of the parent drug within the pharmacopoeial limit. Journal of AOAC International, (2008) In press.
Wahbi A-A, Moneeb M, Hewala I, and Bahnasy M. Application of multivariate methods to the simultaneous Fourier transform infrared (FT-IR) spectrometric determination of stereo-isomers : quinine and quinidine. Chem Pharm Bull, 56(6), (2008).
Abdel-Hay MH, Galal SM and Ragab MA. Stability-Indicating Differential Pulse Polarographic and Derivative Spectrophotometric Determination of Tertrazepam in Presence of its Acid-Induced Degradation Product. Alex J Pharm Sci, 22 (1), pp 51-57, (2008).
Galal SM, Abdel-Hay MH, and Ragab MA. Determination of Rofecoxib By Differential Pulse Polarography. Alex. J Pharm Sci, 22 (1), pp 58-60, (2008).
Galal SM, Abdel-Hay MH, and Ragab MA. Spectrophotometric Determination of Some Drugs Used in the Management of Inflammation and Musculoskeletal Disorders. Bull Fac Pharm Cairo Univ, Vol. 46, No. 1, pp137-152, (2008).
Abdel-Hay MH, Gazy AA, Hassan EM and Belal TS. Derivative and derivative ratio spectrophotometric analysis of antihypertensive ternary mixture of amiloride hydrochloride, hydrochlorothiazide and timolol maleate, Journal of the Chinese Chemical Society (Accepted for Publication, 2008).
Moneeb MS. Chemometric determination of rabeprazole sodium in presence of its acid induced degradation products using spectrophotometry, polarography and anodic voltammetry at a glassy carbon carbon electrode. Pak. J. Pharm. Sci, 21, No. 3, pp 201-209 (2008).
Sabry SM. Study of Forced-Acid/Heat Degradation and Degradant/Impurity Profile of Phenazopyridine Hydrochloride through HPLC and Spectrofluorimetric Analyses, J.Food Drug Anal, 16, pp 54 - 63 (2008).
Maher HM and Youssef RM. Development of Validated Chromatographic Methods for the Simultaneous Determination of Metronidazole and Spiramycin in Tablets. Presented in the Scientific Conference of Faculty of Pharmacy, CairoUniversity, 29 March, 2008.
Youssef RM and Maher HM. Electrochemical Study of Spiramycin and Its Determination in Pharmaceutical Preparations, Presented in the Biovision, Bibliotecha Alexandrina, April, 13-16, (2008) in Alexandria, Egypt.
Belal TS. A simple and sensitive spectrofluorimetric method for analysis of some nitrofuran drugs in pharmaceutical preparations. Accepted for publication in J. Fluoresc.
Belal T, Awad T, DeRuiter J and Randall Clark C. GC–MS studies on acylated derivatives of 3-methoxy-4-methyl- and 4-methoxy-3-methyl-phenethylamines: Regioisomers related to 3,4-MDMA., Forensic Science International, 178(1), pp 61 – 82, (2008).
Awad T, DeRuiter J, Belal T and Randall Clark C. Gas Chromatographic and Mass Spectral Studies on the Acylated Side Chain Regioisomers of 3-Methoxy-4-Methyl Phenethylamine and 4-Methoxy-3-Methyl Phenethylamine. Accepted for publication in J. Chromatog. Sci.
Belal T, Awad T, Randall Clark C and DeRuiter J. GC-MS Evaluation of a Series of Acylated Derivatives of 3,4-Methylenedioxymethamphetamine. Accepted for publication in J. Chromatog. Sci.
Belal T, Awad T and Randall Clark C. Determination of Paracetamol and Tramadol Hydrochloride in Pharmaceutical Mixture Using HPLC and GC-MS. Accepted for publication in J. Chromatog. Sci.
Department of Pharmaceutics
2007 publications
El-Sayed A, Boraie NA, Ismail FA, El-Khordagui LK, and Khalil SA. Assessment of pharmaceutical quality of omeprazole capsule products marketed in Egypt.The Eastern Mediterranean Health Journal, WHO, 13, 6 (2007)*
Etman MA, Nada H, Nada A, Ismail F, Moustafa M and Khalil SA. Preparation and in vitro evaluation of extended release aspirin tablets using air fluidization technique. AAPS Annual Meeting, San Diego, California, USA, 11-17 Nov (2007).
Elsayed MMA, Abdallah OY, Naggar VF and Khalafallah NM. Deformable liposomes and ethososmes as carriers for skin delivery of ketotifen. Pharmazie, 62, pp 133-137 (2007)
Abdelkader H, Abdallah OY and Salem H. Formulation of controlled-release baclofen tablets, influence of some hydrophilic polymers on the release rate and in vitro evaluation. AAPS Pharm Sci Tech, 8(4) article 100 (2007).
Abdelkader H, Abdallah OY and Salem H. Comparison of the effect of trimethomine and polyvinylpyrrolidone on dissolution properties and analgesic effect of nimesulide, AAPS Pharm Sci Tech, 8(3) article 65 (2007).
Nasr MA, Naggar VF. Development of metronidazole colon-specific drug delivery systems. Asian J Pharm Sci, 2, pp 18-28 (2007).
2008 publications
Abdu Y, Abu-Elmagd E, Darwish IA, Nabila A. Boraei NA and El-Khordagui LK. Development of a microbiological SPF determination method.J. Cosmetic Science, August 2008, in press.
Allam AN, Elgamal SS, and Naggar VF. Formulation and evaluation of acyclovir ophthalmic inserts. Asian J Pharm Sci, 3, pp58-67 (2008).
Abdelkader H, Abdallah OY and Salem H. Formulation of controlled-release baclofen matrix tablets. Influence of some hydrophobic excipients on the release rate and in vitro evaluation II. AAPS Pharm Sci Tech (2008), DOI: 10.12081s 12249-008-9094-0.
Etman MA, Nada H, Nada A, Ismail F, Moustafa M and Khalil SA. Prolonged release ketorolac tromethamin loaded non-pareils. 68th International Congress of FIP, Basel, Switzerland, August 29t-Sept. 4, (2008).
Abdelatif M, Yakoot M and Etman M. Safety and efficacy of a new honey ointment on diabetic foot ulcer: a prospective. J. Wound Care, 17(3), pp 108-110 (2008).
Barakat HS, Darwish IA, El-Khordagui LK and Khalafallah NM. Development of naftifine hydrochloride alcohol-free noisome gel. Drug DevInd Pharm, (Accepted) Sept 2008
Department of Industrial Pharmacy
2007 publications
El-Maradny HA. Modulation of pulsatile release drug delivery system using different swellable/rupturable materials. Drug delivery, 14, p 539 (2007)*
Comparative study of inhalable protein dry powders. Innovations in Drug delivery conference, Naples, Italy, 2007
2008 publications
Mortada S. Colon-targeting of mesalazine by coating with cellulose acetate asymmetric membrane coating. Drug Discoveries & Therap. In press 2008.
Mortada S, El-Maradny H, Kamel OA, Hikal AH.. Meloxicam-HPBCD complexes prepared by different techniques, characterization and in vitro evaluation. Alex J Pharm Sci, 2008
Elgendy N. Sonophoretically-enhanced transdermal delivery of testosterone. FIP, Basel, Switzerland, Sept 2008.
Samaha M, El-Maradny HA, Ragab DM and Elkhawas FM. A comparative study of the effect of using different drying techniques for the preparation of inhalable protein powders on their aerosolization performance. Drug. Deliv. Tech., 8(4), 2008.
El-Maradny HA, Preparation and characterization of different binary complexes of carvedilol using freeze-drying technique. Alex J Pharm Sci, (2008).
El-Khodairy and El-Maradny HA. Formulation and release performance and characterization of controlled release oral dosage for of flutamide using hydrogel. Alex J Pharm Sci, (2008)
El-Maradny HA, Samaha MW, and Mehana M. Ciprofloxacin liposomes as vesicular reservoirs for ocular delivery: Formulation, optimization and in vitro characterization. Drug Dev Ind Pharm, (accepted) 2008.
Samaha MW, El-Maradny HA, Ragab DM, and El-Khawas FM. Development and characterization of inhaled formulations for systemic drug delivery. Drug Deliv Technol, (accepted) 2008.
Samaha MW, El-Maradny HA, and Mehana M. Ciprofloxacin reverse phase evaporation liposomes, statistical design for studying different formulation parameters. 1st Scientific Conference of the Faculty of Pharmacy, CairoUniversity, March 2008
Department of Pharmaceutical Chemistry
2007 publications
Shaaban I, El-Khawas S, Mahran M, El-Sayed O, El-Saidi H and Aboul-Enen H. Design, synthesis and evaluation of anticancer activity of novel substituted benzoquinones and hydroquinones Med. Chem. Res., 15 (2007)
Soliman R, Habib NS and Gaber O. Synthesis of thiazolo [4,5-d] pyrimidine derivatives of potential antimicrobial agents. Arch Pharm. Res, 30 (12), 1511 (2007)
Dang HV, Habib NS, Kappe T, Zangger K and stadlbaner W. Synthesis and structure elucidation of 3,4-dihydroxy-2-quinolin-2-yl pyrido[3,2,1-j,k]carbazole-6-ones. J. heterocyclic chemistry, 44, 161-165 (2007)
Shaaban I, El-khawas S, Mahran M, El-sayed OA, El-Saidi H and Aboul-enen H. Design, synthesis and in vitro evaluation of cytotoxic activity of new substituted 1,4-benzoquinones and hydroquinones. Med Chem Research, 16, 49-77 (2007)
Farghaly AM, Aboulwafa OM, El-Semary MA Bekhit AA and El-Shoukrofy. Synthesis of some tetrahydrobenzo[2,3-d]pyrimidinone derivatives of potential pharmacologic activities. 9th Pharmaceutical Conference on Pharmaceutical Chemistry, Riyadh, KSA, Dec 2005*.
Abo-zeid SM, Al–Kanbit M and Aboulwafa OM Structural and biochemical studies of metal complexes with estrone derivatives. 9th Pharmaceutical Conference on Pharmaceutical Chemistry, Riyadh, KSA, Dec 2005*.
Youssef KM, Aboulwafa OM and Al-wably RI Synthesis of bioconjuagate analogs of curcumin as potent antitumor agents. 9th Pharmaceutical Conference on Pharmaceutical Chemistry, Riyadh, KSA, Dec 2005*.
Aboulwafa OM, Al-Mutairi MS , Youssef KM, Al-Subbagh HI, Al-Deeb OA , Al-Alfy AT and Fatani AJ Synthesis of ring A substituted Estrogens of potential therapeutic activity. 19th International Symposium on Medicinal Chemistry, Istanbul, Turkey, Aug-Sept, 2006.
Ahmed M. Farghaly, Omaima M. Aboulwafa, Mona A. EL-Semary, Adnan A.. Bekhit and Mai S. El-ShoukrofySynthesis of some pharmacologically active thiene [3,4-d] pyrimidinone derivatives. 7th Saudi Pharmaceutical International Conference, Riyadh, March 2007.
Aboulwafa OM , Al-Mutairi MS , Youssef KM, Al-Subbagh HI, Al-Deeb OA, Fatani AJ and Al-Okail MS Synthesis of some 2- and 4- peptidylestrone derivatives of potential therapeutic activity. 7th Saudi Pharmaceutical International Conference, Riyadh, March 2007.
Aboulwafa OM, Youssef KM, Al-Obeid AM and Al-Okail MS. Modified Estrogens: synthesis of alkylamino- and alkylthioacetylamino estrone derivatives as potential anticancer agents. 7th Saudi Pharmaceutical International Conference, Riyadh, March 2007.
2008 publication
Rida SM, Ashour FA, El-Hawash SA, El-Semary MM and Badr MH. Synthesis of some novel benzoxazole derivatives and their evaluation as antiangiogenic and antitumor agents. Assiut university 6th international pharmaceutical science conference, March 2008
Rida SM, Youssef AM and Badr MH. Synthesis and evaluation of novel 1,3,4-trisubstituted pyrazole derivatives as antiangiogenic agents. Assiut university 6th international pharmaceutical science conference, March 2008
Saudi MN, Youssef AM, Badr MH, Elbayaa RY, El-Azzouni MZ, Mossallam SF, Baddour NM and Eissa MM. Synthesis of Substituted pyrimidinedione derivatives as Potential Schistosomicidal Agents. 2nd EuCheMS conference September 2008
Youssef AM, Badr MH and Elbayaa RY. Synthesis and Antitumor Activity of 2-Substituted Benzimiazoles. FIP conference, Basel, September 2008
Saudi M.N.S., El-Semary M.M.A, Jaeda M.I., Eissa M.M., Amer E.I. and Baddour N.M. Synthesis and biological evaluation of a novel class as antilieshmanial agents. 2nd EuCheMS conference September 2008
Shafik RM , Soliman FS , El-Semary MM , Saudi MN, and El-Bayaa RY. Novel potential nonsedating H1 antagonists related to the gauche rotamer of PROS-NH-histamine. Med Chem Res (under publication)
Department of Pharmacognosy
2007 publications
Asres K, Mazumder A, El-Fiky F and Bucar F. Chemical composition and antimicrobial activity of the flower essential oil of Solanecio gigas (Vatke) C. Jeffrey. International Journal Of Essential Oil Therapeutics IJEOT, Volume 1 Issue 3 1pp. 135-139 (2007)
Tolossa K, Asres K, El-Fiky FK, Singab A-N and Bucar F. Composition of the Essential Oils of Satureja abyssinica ssp. abyssinica and Satureja paradoxa: Their Antimicrobial and Radical Scavenging Activities. Journal of Essential Oil Research: JEOR, May/Jun 19 pp. 295-300 (2007)
Toaima SM , Radwan MM, Asaad AM and El-Sebakhy NA. Cytotoxic Isoflavones from Calligonum comosum L’her. Bulletin of Faculty of Pharmacy, CairoUniversity, Vol. 45 No.1 2007*
Toaima SM. Phytochemical And Biological Study of the roots of Astragalus peregrinus Vahl Grown in Egypt. Alexandria Journal of Pharmaceutical Sciences, Vol. 21 (2), pp 152-159, (2007)
2008 publications
El-Fiky F, Asres K, Gibbons S, Hammoda H, Badr J and Umer S. Photochemical and antimicrobial investigation of Latex from Euphoria abyssinica Gmmel. Natural products Communications 3 (9), pp 1505-1508 (2008)
Abou-Donia AH, Toaima SM, Hammoda HM, Eman Shawky E, Kinoshita E, Takayama H. Photochemical and Biological Investigation Of Hymenocallis Littoralis SALISB. Chemistry and Biodiversity, Vol. 5, pp 332-340 (2008)
Abou-Donia AH, Toaima SM, Hammoda HM, Shawky E. New Rapid Validated HPTLC Method for the Determination of Galanthamine in Amaryllidaceae Plant Extracts. Photochemical Analysis, 19, pp. 353-358 (2008)
Hammouda HM, Aboul-Ela, El-Hanbali MO, El-Lakany AM, Zaki CS Ghazy NM. Part I: New constituents of Artemisia monosperma Del. Pharmazie, 63, 611 (2008)
Fathy HM, Aboushoer F, Harraz M, Omar AA, Goetz G and Tabacchi R. Dollabellance diterpenes from Cleome droserifolia. Natural products Communications, 3 (9) 1479-1482 (2008).
C.V Pharmacology
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